EEF1B2

Across TCGA patient cohorts, EEF1B2 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1B2-associated genes across cancer lineages are FOXO3a, IRS1, and Annexin-1. Each is linked with EEF1B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1B2-to-partner and partner-to-EEF1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a grouped by EEF1B2-low versus EEF1B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1B2→partner) and Y-score (partner→EEF1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.130	-2.429	.008	.019	3	1
UCEC	IRS1 →	+0.235	+2.459	.019	.020	3	1
UCEC	Annexin-1 →	+0.897	+2.189	<.001	.034	3	1
UCEC	Bak →	+0.266	+3.169	.028	.019	3	1
UCEC	Cyclin-B1 →	+0.622	+2.459	.021	.020	3	1
UCEC	ACVRL1 →	-0.180	-2.439	.006	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

FOXO3a by EEF1B2 expression — UCEC

Explore this box plot interactively →