EEF1AKNMT

Across TCGA patient cohorts, EEF1AKNMT mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1AKNMT-associated genes across cancer lineages are Caspase-7-cleavedD198, beta-Catenin, and ACC_pS79. Each is linked with EEF1AKNMT in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1AKNMT-to-partner and partner-to-EEF1AKNMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by EEF1AKNMT-low versus EEF1AKNMT-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKNMT→partner) and Y-score (partner→EEF1AKNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.353	+3.178	<.001	.010	3	2
UCEC	beta-Catenin →	+0.522	+3.169	.018	.018	3	2
LUSC	ACC_pS79 →	+0.514	+2.821	.007	.035	3	1
UCEC	A-Raf_pS299 →	-0.110	-2.321	.035	.034	3	1
UCEC	Gab2 →	+0.392	+3.321	.011	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.202	-3.169	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Caspase-7-cleavedD198 by EEF1AKNMT expression — COAD

Explore this box plot interactively →