EEF1AKNMT

Across TCGA cell cohorts, EEF1AKNMT mutation is significantly associated with the RNA expression of many other genes, with 214 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EEF1AKNMT-associated genes across cancer lineages are ACP4, CCDC175, and METTL24. Each is linked with EEF1AKNMT in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1AKNMT-to-partner and partner-to-EEF1AKNMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACP4 grouped by EEF1AKNMT-low versus EEF1AKNMT-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKNMT→partner) and Y-score (partner→EEF1AKNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ACP4 →	+0.020	+4.196	<.001	.002	3	1
SKIN	CCDC175 →	+0.139	+4.054	<.001	.004	3	1
SKIN	METTL24 →	+0.246	+3.920	.001	.005	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.036	+4.887	.002	.009	3	1
PANCREAS	CEACAM4 →	+0.043	+4.237	<.001	.006	3	1
PANCREAS	TAAR8 →	+0.017	+4.614	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 214 associations by consensus.

ACP4 by EEF1AKNMT expression — SKIN

Explore this box plot interactively →