EEF1AKMT3

Across TCGA cell cohorts, EEF1AKMT3 mutation is significantly associated with the mutation status of many other genes, with 1,568 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EEF1AKMT3-associated genes across cancer lineages are DNAJA1, BAX, and L2HGDH. Each is linked with EEF1AKMT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1AKMT3-to-partner and partner-to-EEF1AKMT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJA1 grouped by EEF1AKMT3-low versus EEF1AKMT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKMT3→partner) and Y-score (partner→EEF1AKMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DNAJA1 →	+3.459	+3.459	.006	.006	1	1
LARGE_INTESTINE	BAX →	+3.196	+4.793	<.001	<.001	1	1
LARGE_INTESTINE	L2HGDH →	+3.459	+3.459	.006	.006	1	1
LARGE_INTESTINE	NID2 →	+2.459	+4.247	.001	.001	1	1
LARGE_INTESTINE	GNA11 →	+4.044	+3.744	.003	.003	1	1
LARGE_INTESTINE	TPX2 →	+2.874	+3.632	.002	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,568 associations by consensus.

DNAJA1 by EEF1AKMT3 expression — LARGE_INTESTINE

Explore this box plot interactively →