EEF1AKMT2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, EEF1AKMT2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EEF1AKMT2 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EEF1AKMT2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EEF1AKMT2 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where EEF1AKMT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.1771.000.03818view →
LSCCOSQuartileII,III,IV0.9470.525.00117view →
LUADDFSMedianIII,IV0.8290.341.0173view →
PDACOSMedianIV0.2220.973.0383view →
CCRCCDFSMedianAll0.7500.231.0351view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration