EEF1AKMT1

Across TCGA pan-cancer cohorts, EEF1AKMT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EEF1AKMT1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher EEF1AKMT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EEF1AKMT1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where EEF1AKMT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.732	0.930	.002	23	view →
HNSC	OS	Quartile	III,IV	0.761	0.955	.030	5	view →
LUAD	OS	Tertile	II,III,IV	0.394	0.892	.029	2	view →
PDAC	DFS	Tertile	III,IV	1.000	0.516	.040	2	view →
LSCC	DFS	Median	III,IV	0.858	1.000	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

EEF1AKMT1–CCRCC (OS)

Open the CCRCC breakdown →