EEF1AKMT1

Across TCGA patient cohorts, EEF1AKMT1 mutation is significantly associated with the RNA expression of many other genes, with 784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1AKMT1-associated genes across cancer lineages are DEFB108D, SNRPEP10, and MTCO1P56. Each is linked with EEF1AKMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1AKMT1-to-partner and partner-to-EEF1AKMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB108D grouped by EEF1AKMT1-low versus EEF1AKMT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKMT1→partner) and Y-score (partner→EEF1AKMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DEFB108D →	+0.136	+3.260	<.001	.004	3	2
LUSC	SNRPEP10 →	+0.223	+4.287	.005	.008	3	2
COAD	MTCO1P56 →	+0.281	+5.917	<.001	.001	3	2
HNSC	RNU1-112P →	+0.504	+5.822	<.001	.003	3	2
UCEC	NEK4P3 →	+0.102	+2.384	<.001	.002	3	1
UCEC	IGHV3OR16-8 →	+0.785	+2.272	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 784 associations by consensus.

DEFB108D by EEF1AKMT1 expression — UCEC

Explore this box plot interactively →