EEF1A2

Across TCGA pan-cancer cohorts, EEF1A2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EEF1A2 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher EEF1A2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EEF1A2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where EEF1A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.492	0.903	.012	16	view →
CCRCC	DFS	Tertile	IV	0.887	0.198	.024	12	view →
LUAD	DFS	Median	All	0.516	0.942	.006	8	view →
LSCC	OS	Quartile	All	0.753	0.907	.042	6	view →
PDAC	OS	Median	II,III,IV	0.926	0.738	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

EEF1A2–UCEC (OS)

Open the UCEC breakdown →