EEF1A2

Across TCGA patient cohorts, EEF1A2 mutation is significantly associated with the RNA expression of many other genes, with 744 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1A2-associated genes across cancer lineages are AKR1B10P2, PRAMEF25, and SEPTIN7P4. Each is linked with EEF1A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1A2-to-partner and partner-to-EEF1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKR1B10P2 grouped by EEF1A2-low versus EEF1A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A2→partner) and Y-score (partner→EEF1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	AKR1B10P2 →	+0.014	+4.488	<.001	.003	3	3
KIRC	PRAMEF25 →	+0.019	+6.412	<.001	.001	3	2
KIRC	SEPTIN7P4 →	+0.110	+6.184	<.001	.001	3	2
KIRC	MIR6718 →	+0.367	+6.184	<.001	.001	3	2
CESC	LINC02559 →	+0.814	+4.757	<.001	.004	3	2
UCEC	POLDIP3 →	+0.540	+3.711	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 744 associations by consensus.

AKR1B10P2 by EEF1A2 expression — SKCM

Explore this box plot interactively →