EEF1A2

Across TCGA patient cohorts, EEF1A2 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1A2-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and p62 Lck ligand. Each is linked with EEF1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1A2-to-partner and partner-to-EEF1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by EEF1A2-low versus EEF1A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A2→partner) and Y-score (partner→EEF1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.271	-2.999	.020	.035	3	2
UCEC	A-Raf_pS299 →	-0.151	-3.169	.006	.019	3	2
UCEC	p62 Lck ligand →	+0.350	+2.179	.021	.034	3	2
UCEC	TFRC →	+0.546	+2.999	.027	.035	3	2
UCEC	Ku80 →	+0.356	+3.179	.001	.010	3	1
UCEC	PKC-a_pS657 →	+0.375	+1.887	.035	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

EGFR_pY1068 by EEF1A2 expression — UCEC

Explore this box plot interactively →