EEF1A2

Across TCGA cell cohorts, EEF1A2 mutation is significantly associated with the RNA expression of many other genes, with 238 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EEF1A2-associated genes across cancer lineages are RBFA, C1QBP, and NDUFS8. Each is linked with EEF1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1A2-to-partner and partner-to-EEF1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBFA grouped by EEF1A2-low versus EEF1A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A2→partner) and Y-score (partner→EEF1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RBFA →	+0.794	+3.212	.002	.006	3	1
LARGE_INTESTINE	C1QBP →	+0.888	+3.301	<.001	.003	3	1
LARGE_INTESTINE	NDUFS8 →	+0.423	+3.212	.007	.006	3	1
LARGE_INTESTINE	DPH5 →	+0.667	+3.212	<.001	.006	3	1
LARGE_INTESTINE	ELOVL3 →	+0.885	+3.299	<.001	.004	3	1
LARGE_INTESTINE	NDUFAF4 →	+0.661	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 238 associations by consensus.

RBFA by EEF1A2 expression — LARGE_INTESTINE

Explore this box plot interactively →