EEF1A1P9

Across TCGA patient cohorts, EEF1A1P9 mutation is significantly associated with the RNA expression of many other genes, with 3,218 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1A1P9-associated genes across cancer lineages are THAP4, OPA3, and GINS3. Each is linked with EEF1A1P9 in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1A1P9-to-partner and partner-to-EEF1A1P9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THAP4 grouped by EEF1A1P9-low versus EEF1A1P9-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A1P9→partner) and Y-score (partner→EEF1A1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	THAP4 →	+0.544	+3.252	<.001	.009	3	3
UCEC	OPA3 →	+0.444	+2.468	<.001	.001	3	3
UCEC	GINS3 →	+0.552	+2.436	<.001	.002	3	3
SKCM	MUS81 →	+0.447	+3.369	.006	.004	3	2
SKCM	MRPL57 →	+0.436	+3.468	.001	.002	3	2
SKCM	PSMD8 →	+0.438	+3.629	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,218 associations by consensus.

THAP4 by EEF1A1P9 expression — LUSC

Explore this box plot interactively →