EEF1A1P9

Across TCGA patient cohorts, EEF1A1P9 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1A1P9-associated genes across cancer lineages are EGFR, JNK_pT183_Y185, and JNK2. Each is linked with EEF1A1P9 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1A1P9-to-partner and partner-to-EEF1A1P9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by EEF1A1P9-low versus EEF1A1P9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A1P9→partner) and Y-score (partner→EEF1A1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.145	-2.115	.037	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.206	-2.794	.005	.003	3	1
UCEC	JNK2 →	+0.228	+2.817	.008	.036	3	1
UCEC	p70-S6K_pT389 →	-0.206	-2.999	.013	.035	3	1
UCEC	p70-S6K →	+0.167	+2.142	.046	.010	3	1
UCEC	STAT3_pY705 →	-0.368	-2.449	.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

EGFR by EEF1A1P9 expression — UCEC

Explore this box plot interactively →