Across TCGA pan-cancer cohorts, EEF1A1P42 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EEF1A1P42’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where EEF1A1P42 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EEF1A1P42 is over-expressed in tumor, although a few such as PAAD and KICH show the opposite, repressed pattern.
COAD, PAAD, and PRAD are the cancer types where EEF1A1P42 tumor–normal differential expression is most reproducible.