Across TCGA pan-cancer cohorts, EEF1A1P21 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EEF1A1P21’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where EEF1A1P21 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EEF1A1P21 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUAD, COAD, and LUSC are the cancer types where EEF1A1P21 tumor–normal differential expression is most reproducible.