EEF1A1

Across TCGA pan-cancer cohorts, EEF1A1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EEF1A1 data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EEF1A1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EEF1A1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where EEF1A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.925	0.658	.001	24	view →
CCRCC	DFS	Quartile	All	0.376	0.947	.002	20	view →
PDAC	DFS	Tertile	III,IV	0.198	0.600	.012	12	view →
LSCC	DFS	Quartile	II,III,IV	0.887	0.250	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EEF1A1–HNSC (DFS)

Open the HNSC breakdown →