EEF1A1

Across TCGA cell cohorts, EEF1A1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EEF1A1-associated genes across cancer lineages are OR2L5, DIRC1, and FOXB2. Each is linked with EEF1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1A1-to-partner and partner-to-EEF1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L5 grouped by EEF1A1-low versus EEF1A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1A1→partner) and Y-score (partner→EEF1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2L5 →	+0.012	+4.887	.001	.009	3	1
SKIN	DIRC1 →	+0.093	+4.930	<.001	.001	3	1
SKIN	FOXB2 →	+0.029	+4.415	<.001	.007	3	1
SKIN	KRTAP2-1 →	+0.193	+4.415	<.001	.007	3	1
BLOOD_Lymphoma	RNASE11 →	+0.361	+3.736	.008	.009	3	1
BLOOD_Lymphoma	SRY →	+0.014	+4.662	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR2L5 by EEF1A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →