EED

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EED protein abundance is significantly associated with the RNA expression of many other genes, with 13,711 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EED-associated genes across cancer lineages are MYBL2, FAM83D, and FOXM1. Each is linked with EED in more than 7 cancer types. Because this analysis shows association rather than direction, both EED-to-partner and partner-to-EED results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EED versus MYBL2 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EED→partner) and Y-score (partner→EED) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMYBL2 →+1.694+0.210<.001.00138
UCECFAM83D →+1.417+0.210<.001.00138
BRCAFOXM1 →+1.216+0.303<.001<.00138
UCECTIMELESS →+1.028+0.189<.001.00238
UCECMCM3 →+0.979+0.186<.001.00138
BRCANCAPH →+0.875+0.303<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,711 associations by consensus.

EED vs MYBL2 — UCEC

Per-sample scatter of EED vs MYBL2 in UCEC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration