EEA1

Across TCGA patient cohorts, EEA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,108 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EEA1-associated proteins across cancer lineages are CLIP1_S147, METAP2, and PECAM1_S734. Each is linked with EEA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EEA1-to-partner and partner-to-EEA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EEA1 versus CLIP1_S147 in LUAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EEA1→partner) and Y-score (partner→EEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CLIP1_S147 →	+0.406	+0.422	<.001	<.001	3	5
PDAC	METAP2 →	+0.200	+0.264	<.001	.002	3	4
PDAC	PECAM1_S734 →	-0.636	-0.374	<.001	<.001	3	4
PDAC	PTPN11 →	+0.183	+0.385	<.001	<.001	3	4
COAD	CORO1C →	+0.312	+0.388	.003	<.001	3	4
LSCC	CAND1 →	+0.215	+0.442	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,108 associations by consensus.

EEA1 vs CLIP1_S147 — LUAD

Explore this scatter interactively →