EEA1

Across TCGA cell cohorts, EEA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,072 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EEA1-associated GO terms across cancer lineages are Endocytic recycling, Vesicle-mediated transport between endosomal compartments, and Endosomal transport. Each is linked with EEA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both EEA1-to-partner and partner-to-EEA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by EEA1-low versus EEA1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EEA1→partner) and Y-score (partner→EEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endocytic recycling →	+0.065	+0.705	.001	.007	3	17
LUNG_SCLC	Vesicle-mediated transport between endosomal compartments →	+0.053	+0.474	.004	.001	2	15
BONE	Endosomal transport →	+0.065	+1.019	<.001	<.001	3	14
STOMACH	Phosphatidylinositol metabolic process →	+0.058	+0.888	.008	.004	2	15
LUNG_SCLC	Early endosome to late endosome transport →	+0.053	+0.474	.004	.001	2	15
SKIN	Cytosolic transport →	+0.063	+0.842	.003	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

Endocytic recycling by EEA1 expression — BONE

Explore this box plot interactively →