EDRF1

Across TCGA pan-cancer cohorts, EDRF1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EDRF1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EDRF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EDRF1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and CCRCC are the cancer types where EDRF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	1.000	0.888	.005	13	view →
UCEC	DFS	Tertile	III,IV	1.000	0.409	.016	12	view →
CCRCC	OS	Median	III,IV	0.657	1.000	.021	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EDRF1–HNSC (DFS)

Open the HNSC breakdown →