EDRF1

Across TCGA cell cohorts, EDRF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,586 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EDRF1-associated GO terms across cancer lineages are DNA recombination, Regulation of sister chromatid cohesion, and Double-strand break repair. Each is linked with EDRF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both EDRF1-to-partner and partner-to-EDRF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA recombination grouped by EDRF1-low versus EDRF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDRF1→partner) and Y-score (partner→EDRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA recombination →	+0.093	+0.599	.001	.008	3	19
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.151	+1.020	<.001	<.001	3	19
BONE	Double-strand break repair →	+0.089	+0.643	<.001	.004	3	18
BONE	Double-strand break repair via homologous recombination →	+0.098	+0.908	.008	<.001	3	18
OVARY	Positive regulation of double-strand break repair →	+0.086	+0.994	<.001	<.001	3	17
BREAST	Subtelomeric heterochromatin formation →	+0.126	+0.840	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,586 associations by consensus.

DNA recombination by EDRF1 expression — BONE

Explore this box plot interactively →