EDN2

Across TCGA patient cohorts, EDN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,584 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EDN2-associated proteins across cancer lineages are NUB1, CPNE8, and VCL_S272. Each is linked with EDN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EDN2-to-partner and partner-to-EDN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDN2 versus NUB1 in HNSC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN2→partner) and Y-score (partner→EDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUB1 →	-0.229	-1.202	.003	<.001	3	4
BRCA	CPNE8 →	+0.310	+1.230	.006	.004	3	4
PDAC	VCL_S272 →	+0.622	+0.992	<.001	.001	3	3
BRCA	NDRG1 →	+0.525	+1.331	.002	.002	2	4
BRCA	TRAPPC10 →	-0.159	-0.989	.004	.003	3	3
HNSC	PPIP5K1_S944 →	+0.292	+1.210	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,584 associations by consensus.

EDN2 vs NUB1 — HNSC

Explore this scatter interactively →