EDN2

Across TCGA patient cohorts, EDN2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EDN2-associated genes across cancer lineages are MYL9, ACTA2, and DCN. Each is linked with EDN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both EDN2-to-partner and partner-to-EDN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDN2 versus MYL9 in UCEC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN2→partner) and Y-score (partner→EDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.383	+0.626	<.001	<.001	3	10
OV	ACTA2 →	+2.376	+0.756	<.001	<.001	3	10
OV	DCN →	+1.674	+0.625	<.001	<.001	3	10
OV	GLT8D2 →	+1.459	+0.700	<.001	<.001	3	10
UCEC	CNN1 →	+2.736	+0.925	<.001	<.001	3	10
OV	AOC3 →	+1.682	+0.737	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,070 associations by consensus.

EDN2 vs MYL9 — UCEC

Explore this scatter interactively →