EDIL3

Across TCGA patient cohorts, EDIL3 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EDIL3-associated genes across cancer lineages are FASN, mTOR_pS2448, and PDCD4. Each is linked with EDIL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EDIL3-to-partner and partner-to-EDIL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by EDIL3-low versus EDIL3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDIL3→partner) and Y-score (partner→EDIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FASN →	+0.586	+3.000	.008	.034	3	4
UCEC	mTOR_pS2448 →	-0.163	-2.794	<.001	.003	3	3
UCEC	PDCD4 →	-0.546	-2.653	<.001	<.001	3	3
UCEC	eIF4E →	+0.153	+1.716	.025	.003	3	2
UCEC	FOXO3a_pS318_S321 →	-0.096	-1.352	.017	.034	3	2
UCEC	MIG-6 →	+0.065	+1.235	.044	.023	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

FASN by EDIL3 expression — LUAD

Explore this box plot interactively →