EDIL3

Across TCGA cell cohorts, EDIL3 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EDIL3-associated genes across cancer lineages are PPA2, MAD2L1, and THNSL1. Each is linked with EDIL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EDIL3-to-partner and partner-to-EDIL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPA2 grouped by EDIL3-low versus EDIL3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDIL3→partner) and Y-score (partner→EDIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PPA2 →	+0.690	+3.064	.001	.009	3	1
LARGE_INTESTINE	MAD2L1 →	+0.879	+3.064	<.001	.009	3	1
LARGE_INTESTINE	THNSL1 →	+1.054	+3.087	<.001	.006	3	1
LARGE_INTESTINE	CLPSL2 →	+0.599	+3.292	<.001	.006	3	1
LARGE_INTESTINE	PTX4 →	+0.090	+2.743	.001	.005	3	1
LARGE_INTESTINE	ITM2A →	+1.391	+3.215	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PPA2 by EDIL3 expression — LARGE_INTESTINE

Explore this box plot interactively →