EDF1

Across TCGA patient cohorts, EDF1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EDF1-associated genes across cancer lineages are TREM1, TRUB2, and DYNC2I2. Each is linked with EDF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EDF1-to-partner and partner-to-EDF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDF1 versus TREM1 in GBM, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDF1→partner) and Y-score (partner→EDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TREM1 →	-1.302	-0.288	<.001	<.001	3	5
UCEC	TRUB2 →	+0.544	+0.201	.002	.004	3	5
UCEC	DYNC2I2 →	+1.214	+0.220	<.001	.001	3	4
OV	GLE1 →	+0.677	+0.486	<.001	<.001	2	5
OV	NDUFA8 →	+0.727	+0.492	<.001	<.001	3	4
OV	ZWINT →	+0.773	+0.437	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,742 associations by consensus.

EDF1 vs TREM1 — GBM

Explore this scatter interactively →