EDF1

Across TCGA cell cohorts, EDF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,551 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EDF1-associated GO terms across cancer lineages are Dolichol phosphate mannose biosynthetic process, Dolichyl monophosphate biosynthetic process, and Proteasome regulatory particle assembly. Each is linked with EDF1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EDF1-to-partner and partner-to-EDF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dolichol phosphate mannose biosynthetic process grouped by EDF1-low versus EDF1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDF1→partner) and Y-score (partner→EDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Dolichol phosphate mannose biosynthetic process →	+0.056	+0.275	<.001	.009	3	11
LUNG_NSCLC_LUSC	Dolichyl monophosphate biosynthetic process →	+0.127	+0.821	.005	.007	1	11
SOFT_TISSUE	Proteasome regulatory particle assembly →	+0.106	+0.546	<.001	.001	3	9
SOFT_TISSUE	Peptidyl-glycine modification →	+0.172	+0.758	<.001	<.001	3	8
SOFT_TISSUE	Mitochondrial RNA 3'-end processing →	-0.072	-0.523	.005	<.001	3	8
BREAST	CTP salvage →	+0.149	+0.906	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,551 associations by consensus.

Dolichol phosphate mannose biosynthetic process by EDF1 expression — CNS

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