EDEM2

Across TCGA patient cohorts, EDEM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,225 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EDEM2-associated proteins across cancer lineages are NDRG3, PIGT, and AAR2. Each is linked with EDEM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EDEM2-to-partner and partner-to-EDEM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDEM2 versus NDRG3 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDEM2→partner) and Y-score (partner→EDEM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NDRG3 →	+0.493	+0.657	<.001	<.001	3	5
LUAD	PIGT →	+0.306	+0.353	<.001	<.001	3	5
OV	AAR2 →	+0.309	+0.683	.002	<.001	3	5
COAD	CPNE1 →	+0.575	+0.421	<.001	<.001	3	4
OV	DLGAP4 →	+0.258	+0.482	.009	<.001	3	4
COAD	EIF6 →	+0.247	+0.375	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,225 associations by consensus.

EDEM2 vs NDRG3 — OV

Explore this scatter interactively →