EDDM3B

Across TCGA patient cohorts, EDDM3B RNA expression is significantly associated with the protein abundance of many other proteins, with 6,596 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EDDM3B-associated proteins across cancer lineages are MPRIP_S993, TJP1_S912, and ADGRF5. Each is linked with EDDM3B in more than 2 cancer types. Because this analysis shows association rather than direction, both EDDM3B-to-partner and partner-to-EDDM3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDDM3B versus MPRIP_S993 in LUAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDDM3B→partner) and Y-score (partner→EDDM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MPRIP_S993 →	+0.529	+0.752	.006	.007	3	3
LUAD	TJP1_S912 →	+0.702	+0.764	<.001	<.001	3	3
LUAD	ADGRF5 →	+0.633	+0.630	<.001	<.001	3	3
LUAD	SERPINB5 →	-1.372	-0.765	<.001	.002	3	3
BRCA	RBM47 →	+0.281	+0.439	.002	.002	3	3
UCEC	PSMA4_S173 →	-0.586	-0.940	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,596 associations by consensus.

EDDM3B vs MPRIP_S993 — LUAD

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