EDDM3B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EDDM3B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,226 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EDDM3B-associated GO terms across cancer lineages are Mitochondrial membrane organization, Vesicle localization, and Nucleoside triphosphate metabolic process. Each is linked with EDDM3B in more than 8 cancer types. Because this analysis shows association rather than direction, both EDDM3B-to-partner and partner-to-EDDM3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial membrane organization grouped by EDDM3B-low versus EDDM3B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDDM3B→partner) and Y-score (partner→EDDM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADMitochondrial membrane organization →+0.087+0.074<.001<.00139
STADVesicle localization →+0.070+0.071<.001<.00137
STADNucleoside triphosphate metabolic process →+0.089+0.084<.001<.00137
STADPhosphatidylinositol biosynthetic process →+0.069+0.071<.001<.00137
STADRespiratory electron transport chain →+0.097+0.075<.001<.00136
STADIntrinsic apoptotic signaling pathway by p53 class mediator →+0.079+0.061<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,226 associations by consensus.

Mitochondrial membrane organization by EDDM3B expression — STAD

Box plot of Mitochondrial membrane organization in EDDM3B-low vs EDDM3B-high samples in STAD.

Explore this box plot interactively →

Exploration