EDDM3B

Across TCGA cell cohorts, EDDM3B RNA expression is significantly associated with the mutation status of many other genes, with 87 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EDDM3B-associated genes across cancer lineages are ZNF800, PZP, and RUFY1. Each is linked with EDDM3B in more than 1 cancer types. Because this analysis shows association rather than direction, both EDDM3B-to-partner and partner-to-EDDM3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF800 grouped by EDDM3B-low versus EDDM3B-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDDM3B→partner) and Y-score (partner→EDDM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ZNF800 →	+3.734	+0.046	.006	.005	3	2
BLOOD_Lymphoma	PZP →	+4.452	+0.558	.001	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	RUFY1 →	+5.357	+0.043	.003	<.001	3	2
STOMACH	ZNF682 →	+4.285	+0.025	.007	<.001	3	2
PANCREAS	PTPRE →	+4.614	+0.015	.004	<.001	3	1
PANCREAS	WDR81 →	+5.614	+0.020	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

ZNF800 by EDDM3B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →