Across TCGA patient cohorts, EDARADD RNA expression is significantly associated with the protein abundance of many other proteins, with 11,329 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EDARADD-associated proteins across cancer lineages are ERO1B, COL11A1, and COL1A1. Each is linked with EDARADD in more than 4 cancer types. Because this analysis shows association rather than direction, both EDARADD-to-partner and partner-to-EDARADD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDARADD→partner) and Y-score (partner→EDARADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ERO1B →	+0.620	+1.039	.003	<.001	3	5
COAD	COL11A1 →	+0.912	+0.252	.004	.005	3	4
COAD	COL1A1 →	+0.793	+0.248	<.001	<.001	3	4
COAD	COL1A2 →	+0.808	+0.247	<.001	<.001	3	4
CCRCC	BASP1 →	+0.995	+0.443	<.001	<.001	3	4
GBM	STEAP3 →	-0.582	-0.230	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,329 associations by consensus.

Exploration

EDARADD survival (RNA) · tumor vs normal (RNA) · all EDARADD data types