Across TCGA cell cohorts, EDARADD mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EDARADD-associated genes across cancer lineages are OCM2, PSKH2, and PRAMEF11. Each is linked with EDARADD in more than 1 cancer types. Because this analysis shows association rather than direction, both EDARADD-to-partner and partner-to-EDARADD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDARADD→partner) and Y-score (partner→EDARADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.069	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	PSKH2 →	+0.021	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF11 →	+0.006	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

EDARADD survival (RNA) · tumor vs normal (RNA) · all EDARADD data types