ECT2L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ECT2L mutation is significantly associated with the RNA expression of many other genes, with 1,909 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ECT2L-associated genes across cancer lineages are FAM177A1, TAF9, and UHRF1. Each is linked with ECT2L in more than 2 cancer types. Because this analysis shows association rather than direction, both ECT2L-to-partner and partner-to-ECT2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECT2L→partner) and Y-score (partner→ECT2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFAM177A1 →+0.340+1.425<.001.00633
UCECTAF9 →+0.547+2.523<.001<.00132
UCECUHRF1 →+0.770+2.425<.001.00132
SKCMLRR1 →+0.432+2.839.009.00132
SKCMZFYVE19 →+0.359+2.851.007.00132
SKCMSAAL1 →+0.560+2.826.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,909 associations by consensus.

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