Across TCGA patient cohorts, ECT2L mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ECT2L-associated genes across cancer lineages are FOXO3a_pS318_S321, p62 Lck ligand, and Cyclin-B1. Each is linked with ECT2L in more than 1 cancer types. Because this analysis shows association rather than direction, both ECT2L-to-partner and partner-to-ECT2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECT2L→partner) and Y-score (partner→ECT2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.134	-1.797	.002	.025	3	2
UCEC	p62 Lck ligand →	+0.305	+2.125	.008	.010	3	2
UCEC	Cyclin-B1 →	+0.494	+1.362	.012	.037	3	2
UCEC	EGFR_pY1068 →	-0.210	-2.222	.018	.010	3	1
UCEC	JNK2 →	+0.148	+1.662	.034	.011	3	1
UCEC	mTOR_pS2448 →	-0.127	-2.571	.016	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

ECT2L survival (RNA) · tumor vs normal (RNA) · all ECT2L data types