Across TCGA cell cohorts, ECT2L mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ECT2L-associated genes across cancer lineages are OR11H6, FTMT, and CT45A7. Each is linked with ECT2L in more than 1 cancer types. Because this analysis shows association rather than direction, both ECT2L-to-partner and partner-to-ECT2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECT2L→partner) and Y-score (partner→ECT2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR11H6 →	+0.028	+4.930	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
SOFT_TISSUE	CT45A7 →	+0.035	+4.930	<.001	.008	3	1
SKIN	INSL4 →	+0.349	+3.791	.001	.007	3	1
SKIN	ODF1 →	+0.013	+4.022	<.001	.006	3	1
SKIN	SHCBP1L →	+0.027	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ECT2L survival (RNA) · tumor vs normal (RNA) · all ECT2L data types