ECT2

Across TCGA cell cohorts, ECT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,857 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ECT2-associated GO terms across cancer lineages are Regulation of centriole replication, Positive regulation of chromosome condensation, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with ECT2 in more than 18 cancer types. Because this analysis shows association rather than direction, both ECT2-to-partner and partner-to-ECT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole replication grouped by ECT2-low versus ECT2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECT2→partner) and Y-score (partner→ECT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of centriole replication →	+0.100	+1.003	<.001	.007	3	19
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.258	+1.347	<.001	<.001	3	19
OESOPHAGUS	Immunoglobulin heavy chain V-D-J recombination →	+0.280	+1.220	<.001	.001	3	18
SKIN	Microtubule cytoskeleton organization involved in mitosis →	+0.120	+1.247	<.001	<.001	3	17
PANCREAS	Protein localization to condensed chromosome →	+0.152	+1.112	<.001	<.001	3	17
OESOPHAGUS	Nuclear division →	+0.100	+0.990	<.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,857 associations by consensus.

Regulation of centriole replication by ECT2 expression — URINARY_TRACT

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