ECSIT

Across TCGA patient cohorts, ECSIT RNA expression is significantly associated with the protein abundance of many other proteins, with 20,739 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ECSIT-associated proteins across cancer lineages are RAVER1, KRI1, and HDGFL2. Each is linked with ECSIT in more than 7 cancer types. Because this analysis shows association rather than direction, both ECSIT-to-partner and partner-to-ECSIT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECSIT versus RAVER1 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECSIT→partner) and Y-score (partner→ECSIT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAVER1 →	+0.346	+0.679	<.001	<.001	3	8
OV	KRI1 →	+0.579	+0.691	<.001	<.001	3	7
GBM	HDGFL2 →	+0.388	+0.441	<.001	<.001	3	6
LSCC	KEAP1 →	+0.623	+0.756	<.001	<.001	3	6
OV	KRI1_S628 →	+0.647	+0.749	<.001	<.001	3	6
OV	PIN1 →	+0.401	+0.687	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,739 associations by consensus.

ECSIT vs RAVER1 — OV

Explore this scatter interactively →