ECSIT

Across TCGA patient cohorts, ECSIT protein abundance is significantly associated with the RNA expression of many other genes, with 13,832 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ECSIT-associated genes across cancer lineages are ENTPD1, IRF8, and GPR174. Each is linked with ECSIT in more than 5 cancer types. Because this analysis shows association rather than direction, both ECSIT-to-partner and partner-to-ECSIT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECSIT versus ENTPD1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECSIT→partner) and Y-score (partner→ECSIT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ENTPD1 →	-0.574	-0.277	.004	<.001	3	6
BRCA	IRF8 →	-0.862	-0.383	<.001	<.001	3	6
LSCC	GPR174 →	-0.907	-0.505	<.001	<.001	3	6
BRCA	FLI1 →	-0.670	-0.350	<.001	<.001	3	6
LUAD	PYHIN1 →	-0.674	-0.203	<.001	.005	3	6
BRCA	PCED1B-AS1 →	-0.748	-0.346	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,832 associations by consensus.

ECSIT vs ENTPD1 — UCEC

Explore this scatter interactively →