ECM1

Across TCGA patient cohorts, ECM1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,381 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ECM1-associated genes across cancer lineages are COL5A1, MFAP5, and MYL9. Each is linked with ECM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ECM1-to-partner and partner-to-ECM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECM1 versus COL5A1 in OV, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECM1→partner) and Y-score (partner→ECM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL5A1 →	+2.079	+0.721	<.001	<.001	3	9
BRCA	MFAP5 →	+1.828	+0.738	<.001	<.001	3	9
UCEC	MYL9 →	+1.175	+0.457	<.001	<.001	3	8
OV	MEIS3 →	+1.266	+0.891	<.001	<.001	3	8
LSCC	COL12A1 →	+1.300	+0.591	<.001	<.001	3	8
OV	LAMA4 →	+1.154	+0.759	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,381 associations by consensus.

ECM1 vs COL5A1 — OV

Explore this scatter interactively →