Across TCGA patient cohorts, ECI2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,866 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ECI2-associated genes across cancer lineages are C6orf201, ECI2-DT, and KCTD17. Each is linked with ECI2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ECI2-to-partner and partner-to-ECI2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI2→partner) and Y-score (partner→ECI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C6orf201 →	+0.744	+0.700	<.001	<.001	3	8
UCEC	ECI2-DT →	+0.612	+0.999	<.001	<.001	3	6
OV	KCTD17 →	-0.749	-0.654	<.001	.002	3	4
OV	PLAU →	-1.451	-0.530	<.001	.001	3	4
OV	LIF →	-1.036	-0.454	<.001	<.001	3	4
UCEC	FRMD6 →	-0.699	-0.636	.008	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,866 associations by consensus.

Exploration

ECI2 survival (RNA) · tumor vs normal (RNA) · all ECI2 data types