Across TCGA cell cohorts, ECI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,201 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ECI2-associated GO terms across cancer lineages are Regulation of glutamate secretion, neurotransmission, Serotonin secretion, and Serotonin production involved in inflammatory response. Each is linked with ECI2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ECI2-to-partner and partner-to-ECI2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI2→partner) and Y-score (partner→ECI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of glutamate secretion, neurotransmission →	+0.174	+1.752	.003	.001	3	12
BLOOD_Lymphoma	Serotonin secretion →	-1.136	-1.344	<.001	<.001	3	11
BLOOD_Lymphoma	Serotonin production involved in inflammatory response →	-1.136	-1.344	<.001	<.001	3	11
BLOOD_Lymphoma	Serotonin secretion involved in inflammatory response →	-1.136	-1.344	<.001	<.001	3	11
BREAST	Protein localization to ciliary membrane →	+0.087	+1.183	<.001	.004	3	10
PANCREAS	Response to molecule of fungal origin →	-1.215	-1.148	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

Exploration

ECI2 survival (RNA) · tumor vs normal (RNA) · all ECI2 data types