ECHS1

Across TCGA patient cohorts, ECHS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,557 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ECHS1-associated proteins across cancer lineages are GLRX3, XPNPEP1, and PRDX3. Each is linked with ECHS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ECHS1-to-partner and partner-to-ECHS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHS1 versus GLRX3 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHS1→partner) and Y-score (partner→ECHS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GLRX3 →	+0.412	+0.528	<.001	<.001	3	6
COAD	XPNPEP1 →	+0.385	+0.590	<.001	<.001	3	5
GBM	PRDX3 →	+0.308	+0.227	<.001	<.001	3	4
GBM	PWWP2B_S206 →	+0.494	+0.269	<.001	<.001	3	4
LUAD	RPL4_S295 →	+0.967	+0.315	<.001	.001	3	4
OV	ABRAXAS2 →	+0.314	+0.573	<.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,557 associations by consensus.

ECHS1 vs GLRX3 — LSCC

Explore this scatter interactively →