ECHS1

Across TCGA patient cohorts, ECHS1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,008 significant associations in total. OV shows the largest number of these associations.

The most reproducible ECHS1-associated genes across cancer lineages are TCF19, SLC43A3, and TUBB. Each is linked with ECHS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ECHS1-to-partner and partner-to-ECHS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHS1 versus TCF19 in LUAD, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHS1→partner) and Y-score (partner→ECHS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TCF19 →	-0.830	-0.334	<.001	.001	3	6
UCEC	SLC43A3 →	-1.037	-0.433	<.001	<.001	3	6
BRCA	TUBB →	-0.727	-0.575	<.001	<.001	3	6
OV	LINC01943 →	-0.607	-0.489	<.001	.001	3	6
BRCA	MPP7 →	+0.975	+0.386	.002	.001	3	6
BRCA	HIF1A →	-0.630	-0.372	.005	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,008 associations by consensus.

ECHS1 vs TCF19 — LUAD

Explore this scatter interactively →