ECHDC3

Across TCGA cell cohorts, ECHDC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,150 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ECHDC3-associated GO terms across cancer lineages are Purine ribonucleotide metabolic process, Ribonucleotide metabolic process, and Ribonucleoside triphosphate biosynthetic process. Each is linked with ECHDC3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ECHDC3-to-partner and partner-to-ECHDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide metabolic process grouped by ECHDC3-low versus ECHDC3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC3→partner) and Y-score (partner→ECHDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Purine ribonucleotide metabolic process →	+0.030	+0.855	.003	.003	3	7
LUNG_NSCLC_LUAD	Ribonucleotide metabolic process →	+0.044	+1.187	<.001	.001	3	7
OVARY	Ribonucleoside triphosphate biosynthetic process →	+0.092	+1.962	<.001	<.001	3	7
OVARY	Cytoplasmic translation →	+0.070	+1.659	.002	.001	3	7
OVARY	Aerobic electron transport chain →	+0.100	+1.530	<.001	<.001	3	6
PANCREAS	Ribose phosphate biosynthetic process →	+0.063	+1.578	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,150 associations by consensus.

Purine ribonucleotide metabolic process by ECHDC3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →