ECHDC2

Across TCGA patient cohorts, ECHDC2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,493 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ECHDC2-associated genes across cancer lineages are YEATS2, UBE2S, and FOXM1. Each is linked with ECHDC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ECHDC2-to-partner and partner-to-ECHDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHDC2 versus YEATS2 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC2→partner) and Y-score (partner→ECHDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	YEATS2 →	-0.549	-0.230	<.001	<.001	3	5
BRCA	UBE2S →	-1.095	-0.620	<.001	<.001	3	5
BRCA	FOXM1 →	-1.064	-0.467	<.001	<.001	3	5
BRCA	NCAPH →	-1.159	-0.856	<.001	<.001	3	5
BRCA	SKA1 →	-1.013	-0.415	<.001	<.001	3	5
BRCA	PRR11 →	-1.076	-0.666	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,493 associations by consensus.

ECHDC2 vs YEATS2 — LSCC

Explore this scatter interactively →