ECHDC2

Across TCGA cell cohorts, ECHDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,218 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ECHDC2-associated GO terms across cancer lineages are Fatty acid catabolic process, Post-Golgi vesicle-mediated transport, and Phospholipid biosynthetic process. Each is linked with ECHDC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ECHDC2-to-partner and partner-to-ECHDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid catabolic process grouped by ECHDC2-low versus ECHDC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC2→partner) and Y-score (partner→ECHDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.100	+2.771	<.001	<.001	3	14
OVARY	Post-Golgi vesicle-mediated transport →	+0.048	+1.498	.002	.005	3	13
OVARY	Phospholipid biosynthetic process →	+0.041	+2.082	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.084	+2.338	<.001	<.001	3	12
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.111	+1.966	<.001	<.001	3	12
SOFT_TISSUE	Striated muscle contraction →	+0.055	+1.177	.003	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,218 associations by consensus.

Fatty acid catabolic process by ECHDC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →