ECHDC1

Across TCGA patient cohorts, ECHDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,625 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ECHDC1-associated genes across cancer lineages are ACKR1, SAMHD1, and NAPSB. Each is linked with ECHDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ECHDC1-to-partner and partner-to-ECHDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHDC1 versus ACKR1 in BRCA, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC1→partner) and Y-score (partner→ECHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ACKR1 →	+1.551	+0.401	<.001	.006	3	6
HNSC	SAMHD1 →	+0.826	+0.453	<.001	<.001	3	6
UCEC	NAPSB →	+1.261	+0.263	.002	<.001	3	6
GBM	TROAP →	-1.105	-0.516	<.001	<.001	3	6
GBM	BRIP1 →	-1.060	-0.531	<.001	<.001	3	6
HNSC	NEMP1 →	-0.919	-0.344	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,625 associations by consensus.

ECHDC1 vs ACKR1 — BRCA

Explore this scatter interactively →