ECHDC1

Across TCGA cell cohorts, ECHDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,024 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ECHDC1-associated GO terms across cancer lineages are Spermidine biosynthetic process, Spermine biosynthetic process, and 7-methylguanosine mRNA capping. Each is linked with ECHDC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ECHDC1-to-partner and partner-to-ECHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermidine biosynthetic process grouped by ECHDC1-low versus ECHDC1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC1→partner) and Y-score (partner→ECHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Spermidine biosynthetic process →	+0.136	+0.697	.001	.001	3	16
BREAST	Spermine biosynthetic process →	+0.157	+2.116	.002	.009	2	15
OVARY	7-methylguanosine mRNA capping →	+0.133	+1.339	<.001	<.001	3	12
OVARY	7-methylguanosine RNA capping →	+0.133	+1.339	<.001	<.001	3	12
KIDNEY	Negative regulation of ubiquitin protein ligase activity →	+0.275	+1.085	<.001	<.001	3	12
KIDNEY	Regulation of mitochondrial transcription →	+0.092	+0.739	.003	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,024 associations by consensus.

Spermidine biosynthetic process by ECHDC1 expression — LIVER

Explore this box plot interactively →